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Acrolein-Exposed Normal Human Lung Fibroblasts in Vitro: Cellular Senescence, Enhanced Telomere Erosion, and Degradation of Werner’s Syndrome Protein

Background: Acrolein is a ubiquitous environmental hazard to human health. Acrolein has been reported to activate the DNA damage response and induce apoptosis. However, little is known about the effects of acrolein on cellular senescence. Objectives: We examined whether acrolein induces cellular sen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jang, Jun-Ho, Bruse, Shannon, Huneidi, Salam, Schrader, Ronald M., Monick, Martha M., Lin, Yong, Carter, A. Brent, Klingelhutz, Aloysius J., Nyunoya, Toru
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: NLM-Export 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154210/
https://ncbi.nlm.nih.gov/pubmed/24747221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1306911
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