Acrolein-Exposed Normal Human Lung Fibroblasts in Vitro: Cellular Senescence, Enhanced Telomere Erosion, and Degradation of Werner’s Syndrome Protein

Background: Acrolein is a ubiquitous environmental hazard to human health. Acrolein has been reported to activate the DNA damage response and induce apoptosis. However, little is known about the effects of acrolein on cellular senescence. Objectives: We examined whether acrolein induces cellular sen...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Jang, Jun-Ho, Bruse, Shannon, Huneidi, Salam, Schrader, Ronald M., Monick, Martha M., Lin, Yong, Carter, A. Brent, Klingelhutz, Aloysius J., Nyunoya, Toru
Materialtyp: Artigo
Språk:Inglês
Publicerad: NLM-Export 2014
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154210/
https://ncbi.nlm.nih.gov/pubmed/24747221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1306911
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk