Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone

Testosterone (T) stimulates erythropoiesis and regulates iron homeostasis. However, it remains unknown whether the (type II) 5α-reduction of T to dihydrotestosterone (DHT) mediates these androgenic effects, as it does in some other tissues. Our purpose was to determine whether inhibition of type II...

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Главные авторы: Beggs, Luke A., Yarrow, Joshua F., Conover, Christine F., Meuleman, John R., Beck, Darren T., Morrow, Matthew, Zou, Baiming, Shuster, Jonathan J., Borst, Stephen E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154071/
https://ncbi.nlm.nih.gov/pubmed/25074984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00184.2014
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