Musculoskeletal and prostate effects of combined testosterone and finasteride administration in older hypogonadal men: a randomized, controlled trial

Testosterone acts directly at androgen receptors and also exerts potent actions following 5α-reduction to dihydrotestosterone (DHT). Finasteride (type II 5α-reductase inhibitor) lowers DHT and is used to treat benign prostatic hyperplasia. However, it is unknown whether elevated DHT mediates either...

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Hlavní autoři: Borst, Stephen E., Yarrow, Joshua F., Conover, Christine F., Nseyo, Unyime, Meuleman, John R., Lipinska, Judyta A., Braith, Randy W., Beck, Darren T., Martin, Jeffrey S., Morrow, Matthew, Roessner, Shirley, Beggs, Luke A., McCoy, Sean C., Cannady, Darryl F., Shuster, Jonathan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073894/
https://ncbi.nlm.nih.gov/pubmed/24326421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00592.2013
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