α7 Nicotinic Acetylcholine Receptor Signaling Inhibits Inflammasome Activation by Preventing Mitochondrial DNA Release

The mammalian immune system and the nervous system coevolved under the influence of cellular and environmental stress. Cellular stress is associated with changes in immunity and activation of the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome, a key component of innate immunity...

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Bibliografiske detaljer
Main Authors: Lu, Ben, Kwan, Kevin, Levine, Yaakov A, Olofsson, Peder S, Yang, Huan, Li, Jianhua, Joshi, Sonia, Wang, Haichao, Andersson, Ulf, Chavan, Sangeeta S, Tracey, Kevin J
Format: Artigo
Sprog:Inglês
Udgivet: ScholarOne 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153835/
https://ncbi.nlm.nih.gov/pubmed/24849809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2013.00117
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