Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy

AIMS: Kidney cells in patients with diabetic nephropathy are reported to be senescent. However, the mechanisms that regulate cellular senescence in the diabetic kidney are still unknown. In the present study, we evaluated the contribution of high glucose to renal cell senescence in streptozotocin (S...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kitada, Kento, Nakano, Daisuke, Ohsaki, Hiroyuki, Hitomi, Hirofumi, Minamino, Tohru, Yatabe, Junichi, Felder, Robin A., Mori, Hirohito, Masaki, Tsutomu, Kobori, Hiroyuki, Nishiyama, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153757/
https://ncbi.nlm.nih.gov/pubmed/24996978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdiacomp.2014.05.010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados