Aldosterone Does Not Contribute to Renal p21 Expression During the Development of Angiotensin II-Induced Hypertension in Mice

BACKGROUND: We recently reported that aldosterone-induced cellular senescence via an increase in p21, a cyclin-dependent kinase (CDK) inhibitor, in rat kidney and cultured human proximal tubular cells. In the present study, we investigated the contribution of aldosterone to the renal p21 expression...

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Detalhes bibliográficos
Main Authors: Nakano, Daisuke, Lei, Bai, Kitada, Kento, Hitomi, Hirofumi, Kobori, Hiroyuki, Mori, Hirohito, Deguchi, Kazushi, Masaki, Tsutomu, Minamino, Tohru, Nishiyama, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288356/
https://ncbi.nlm.nih.gov/pubmed/22113172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2011.224
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