The Interferon-Induced Gene Ifi27l2a is Active in Lung Macrophages and Lymphocytes After Influenza A Infection but Deletion of Ifi27l2a in Mice Does Not Increase Susceptibility to Infection

Interferons represent one of the first and essential host defense mechanisms after infection, and the activation of the IFN-pathway results in the transcriptional activation of hundreds of interferon-stimulated genes. The alpha-inducible protein 27 like 2A (Ifi27l2a) gene (human synonym: ISG12) is s...

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Main Authors: Tantawy, Mohamed A., Hatesuer, Bastian, Wilk, Esther, Dengler, Leonie, Kasnitz, Nadine, Weiß, Siegfried, Schughart, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153650/
https://ncbi.nlm.nih.gov/pubmed/25184786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106392
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