Rho Family Guanine Nucleotide Exchange Factor Brx Couples Extracellular Signals to the Glucocorticoid Signaling System

Glucocorticoids regulate many crucial biologic functions through their cytoplasmic/nuclear glucocorticoid receptors (GR). Excess, deficiency, or alteration in tissue sensitivity to glucocorticoids has been associated with major causes of human morbidity and mortality. Brx, a cytoplasmic Rho family g...

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Hlavní autoři: Kino, Tomoshige, Souvatzoglou, Emanuel, Charmandari, Evangelia, Ichijo, Takamasa, Driggers, Paul, Mayers, Chantal, Alatsatianos, Anton, Manoli, Irini, Westphal, Heiner, Chrousos, George P., Segars, James H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152920/
https://ncbi.nlm.nih.gov/pubmed/16469733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M509339200
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