The Rho Guanine Nucleotide Exchange Factor AKAP13 (BRX) Is Essential for Cardiac Development in Mice

A fundamental biologic principle is that diverse biologic signals are channeled through shared signaling cascades to regulate development. Large scaffold proteins that bind multiple proteins are capable of coordinating shared signaling pathways to provide specificity to activation of key development...

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Autores principales: Mayers, Chantal M., Wadell, Jennifer, McLean, Kate, Venere, Monica, Malik, Minnie, Shibata, Takahisa, Driggers, Paul H., Kino, Tomoshige, Guo, X. Catherine, Koide, Hisashi, Gorivodsky, Marat, Grinberg, Alex, Mukhopadhyay, Mahua, Abu-Asab, Mones, Westphal, Heiner, Segars, James H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852973/
https://ncbi.nlm.nih.gov/pubmed/20139090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106856
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