Generalized Glucocorticoid Resistance: Clinical Aspects, Molecular Mechanisms, and Implications of a Rare Genetic Disorder

Context: Primary generalized glucocorticoid resistance is a rare genetic condition characterized by generalized, partial, target-tissue insensitivity to glucocorticoids. We review the clinical aspects, molecular mechanisms, and implications of this disorder. Evidence Acquisition: We conducted a syst...

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Bibliographic Details
Main Authors: Charmandari, Evangelia, Kino, Tomoshige, Ichijo, Takamasa, Chrousos, George P.
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2008
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386273/
https://ncbi.nlm.nih.gov/pubmed/18319312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-0040
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