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The Proto-oncoprotein Brx Activates Estrogen Receptor β by a p38 Mitogen-activated Protein Kinase Pathway

The estrogen receptors (ERs) are ligand-inducible transcription factors that play key roles in the control of growth and differentiation in reproductive tissues. We showed that the novel Dbl family proto-oncoprotein Brx enhances ligand-dependent activity of ERα via a Cdc42-dependent pathway. Brx als...

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Detalhes bibliográficos
Main Authors: Driggers, Paul H., Segars, James H., Rubino, Domenica M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152864/
https://ncbi.nlm.nih.gov/pubmed/11579095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M106927200
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