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Autophagy regulation: RNF2 targets AMBRA1

The phosphatidylinositol 3-kinase complex I (PI3K complex I) is a crucial regulator of autophagy, which contains Beclin 1 (or ATG6), ATG14L, VPS34 (or the class III phosphatidylinositol 3-kinase and its adaptor VPS15) and AMBRA1, and controls autophagosome formation. In a paper recently published in...

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Détails bibliographiques
Auteurs principaux: Morel, Etienne, Dupont, Nicolas, Codogno, Patrice
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152733/
https://ncbi.nlm.nih.gov/pubmed/25104734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.105
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