Autophagy is activated in systemic lupus erythematosus and required for plasmablast development

BACKGROUND: Autophagy has emerged as a critical homeostatic mechanism in T lymphocytes, influencing proliferation and differentiation. Autophagy in B cells has been less studied, but genetic deficiency causes impairment of early and late developmental stages OBJECTIVES: To explore the role of autoph...

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Bibliographische Detailangaben
Hauptverfasser: Clarke, Alexander J, Ellinghaus, Ursula, Cortini, Andrea, Stranks, Amanda, Simon, Anna Katharina, Botto, Marina, Vyse, Timothy J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2015
Schlagworte:
Basic and Translational Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152192/
https://ncbi.nlm.nih.gov/pubmed/24419333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-204343
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