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In vivo evidence for apoptosis in the bone marrow in systemic lupus erythematosus

An increase in leucocyte apoptosis and impaired clearance of apoptotic cells has been observed in patients with systemic lupus erythematosus (SLE). Apoptotic cells are likely to be a key source of autoantigens in SLE as they express many of the nuclear autoantigens (in surface blebs and apoptotic bo...

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Hlavní autoři: Hepburn, Alastair L, Lampert, Irvin A, Boyle, Joseph J, Horncastle, Donna, Ng, W Fai, Layton, Mark, Vyse, Timothy J, Botto, Marina, Mason, Justin C
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1954716/
https://ncbi.nlm.nih.gov/pubmed/17277002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.065003
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