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Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia–cell cycle dual reporter

Although aerobic glycolysis provides an advantage in the hypoxic tumor microenvironment, some cancer cells can also respire via oxidative phosphorylation. These respiring (“non-Warburg”) cells were previously thought not to play a key role in tumorigenesis and thus fell from favor in the literature....

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Main Authors: Le, Anne, Stine, Zachary E., Nguyen, Christopher, Afzal, Junaid, Sun, Peng, Hamaker, Max, Siegel, Nicholas M., Gouw, Arvin M., Kang, Byung-hak, Yu, Shu-Han, Cochran, Rory L., Sailor, Kurt A., Song, Hongjun, Dang, Chi V.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151727/
https://ncbi.nlm.nih.gov/pubmed/25114222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402012111
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