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Genetics of pain perception, COMT and postoperative pain management in children

BACKGROUND: Effective perioperative analgesia is lacking for children owing to interindividual variations and underdosing of opioids caused by fear of adverse effects. We investigated the role of COMT SNPs on postoperative pain management in children. METHODS: One hundred and forty nine children und...

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Main Authors: Sadhasivam, Senthilkumar, Chidambaran, Vidya, Olbrecht, Vanessa A, Esslinger, Hope R, Zhang, Kejian, Zhang, Xue, Martin, Lisa J
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151110/
https://ncbi.nlm.nih.gov/pubmed/24533707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.13.248
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