Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots

The suitability of the capillary dried blood spot (DBS) sampling method was assessed for simultaneous phenotyping of cytochrome P450 (CYP) enzymes and P-glycoprotein (P-gp) using a cocktail approach. Ten volunteers received an oral cocktail capsule containing low doses of the probes bupropion (CYP2B...

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Hauptverfasser: Bosilkovska, M, Samer, C F, Déglon, J, Rebsamen, M, Staub, C, Dayer, P, Walder, B, Desmeules, J A, Daali, Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151019/
https://ncbi.nlm.nih.gov/pubmed/24722393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2014.83
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