mRNA-based vaccines synergize with radiation therapy to eradicate established tumors

BACKGROUND: The eradication of large, established tumors by active immunotherapy is a major challenge because of the numerous cancer evasion mechanisms that exist. This study aimed to establish a novel combination therapy consisting of messenger RNA (mRNA)-based cancer vaccines and radiation, which...

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Bibliografiske detaljer
Main Authors: Fotin-Mleczek, Mariola, Zanzinger, Kai, Heidenreich, Regina, Lorenz, Christina, Kowalczyk, Aleksandra, Kallen, Karl-Josef, Huber, Stephan M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150951/
https://ncbi.nlm.nih.gov/pubmed/25127546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-9-180
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