Phase Ib study evaluating a self-adjuvanted mRNA cancer vaccine (RNActive®) combined with local radiation as consolidation and maintenance treatment for patients with stage IV non-small cell lung cancer

BACKGROUND: Advanced non-small cell lung cancer (NSCLC) represents a significant unmet medical need. Despite advances with targeted therapies in a small subset of patients, fewer than 20% of patients survive for more than two years after diagnosis. Cancer vaccines are a promising therapeutic approac...

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Autors principals: Sebastian, Martin, Papachristofilou, Alexandros, Weiss, Christian, Früh, Martin, Cathomas, Richard, Hilbe, Wolfgang, Wehler, Thomas, Rippin, Gerd, Koch, Sven D, Scheel, Birgit, Fotin-Mleczek, Mariola, Heidenreich, Regina, Kallen, Karl-Josef, Gnad-Vogt, Ulrike, Zippelius, Alfred
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Study Protocol
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195907/
https://ncbi.nlm.nih.gov/pubmed/25288198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-748
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