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Transcription Factor- Plasmid Binding Modulates Microtubule Interactions and Intracellular Trafficking During Gene Transfer
For non-viral gene delivery to be successful, plasmids must move through the cytoplasm to the nucleus in order to be transcribed. While the cytoskeletal meshwork acts as a barrier to plasmid DNA movement in the cytoplasm, the microtubule network is required for directed plasmid trafficking to the nu...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150871/ https://ncbi.nlm.nih.gov/pubmed/21716302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.96 |
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