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EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosis

The function of EspI, a 70-kDa protein in Mycobacterium tuberculosis, has remained unclear. Although EspI is encoded by a gene within the esx-1 locus, in this study we clarify previous conflicting results and show that EspI is not essential for ESX-1-mediated secretion or virulence in M. tuberculosi...

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Bibliografiske detaljer
Main Authors: Zhang, Ming, Chen, Jeffrey M., Sala, Claudia, Rybniker, Jan, Dhar, Neeraj, Cole, Stewart T.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150839/
https://ncbi.nlm.nih.gov/pubmed/25039394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12718
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