Učitavanje...
The Effect of CYP2D6 Drug-Drug Interactions on Hydrocodone Effectiveness
OBJECTIVES: The hepatic cytochrome 2D6 (CYP2D6) is a saturable enzyme responsible for metabolism of approximately 25% of known pharmaceuticals. CYP interactions can alter the efficacy of prescribed medications. Hydrocodone is largely dependent on CYP2D6 metabolism for analgesia, ondansetron is inact...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150819/ https://ncbi.nlm.nih.gov/pubmed/25156930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acem.12431 |
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