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Architectural proteins CTCF and cohesin have distinct roles in modulating the higher order structure and expression of the CFTR locus

Higher order chromatin structures across the genome are maintained in part by the architectural proteins CCCTC binding factor (CTCF) and the cohesin complex, which co-localize at many sites across the genome. Here, we examine the role of these proteins in mediating chromatin structure at the cystic...

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Main Authors: Gosalia, Nehal, Neems, Daniel, Kerschner, Jenny L., Kosak, Steven T., Harris, Ann
格式: Artigo
語言:Inglês
出版: Oxford University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150766/
https://ncbi.nlm.nih.gov/pubmed/25081205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku648
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