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p75(NTR) is highly expressed in vestibular schwannomas and promotes cell survival by activating NF-κB
Vestibular schwannomas (VSs) arise from Schwann cells (SCs) and result from the loss of function of merlin, the protein product of the NF2 tumor suppressor gene. In contrast to non-neoplastic SCs, VS cells survive long-term in the absence of axons. We find that p75(NTR) is over-expressed in VSs comp...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150679/ https://ncbi.nlm.nih.gov/pubmed/24976126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22709 |
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