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Inhibition of c-Jun N-terminal kinase activity enhances vestibular schwannoma cell sensitivity to γ-irradiation
BACKGROUND: Radiosurgery is increasingly used to treat vestibular schwannomas (VSs). Increasing the sensitivity of VS cells to irradiation (IR) could allow for lower and/or more effective doses of IR, improving safety and efficacy. Persistent JNK activity in VS cells reduces cell death by suppressin...
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| Publicado no: | Neurosurgery |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4313352/ https://ncbi.nlm.nih.gov/pubmed/23728448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/01.neu.0000431483.10031.89 |
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