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Inhibition of c-Jun N-terminal kinase activity enhances vestibular schwannoma cell sensitivity to γ-irradiation

BACKGROUND: Radiosurgery is increasingly used to treat vestibular schwannomas (VSs). Increasing the sensitivity of VS cells to irradiation (IR) could allow for lower and/or more effective doses of IR, improving safety and efficacy. Persistent JNK activity in VS cells reduces cell death by suppressin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurosurgery
Egile Nagusiak: Yue, Wei Ying, Clark, J. Jason, Telisak, Michael, Hansen, Marlan R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313352/
https://ncbi.nlm.nih.gov/pubmed/23728448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/01.neu.0000431483.10031.89
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