Merlin status regulates p75(NTR) expression and apoptotic signaling in Schwann cells following nerve injury

After nerve injury, Schwann cells (SCs) dedifferentiate, proliferate, and support axon regrowth. If axons fail to regenerate, denervated SCs eventually undergo apoptosis due, in part, to increased expression of the low-affinity neurotrophin receptor, p75(NTR). Merlin is the protein product of the NF...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Ahmad, Iram, Fernando, Augusta, Gurgel, Richard, Clark, J. Jason, Xu, Linjing, Hansen, Marlan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641051/
https://ncbi.nlm.nih.gov/pubmed/26057084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.05.021
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