Interaction between PNPLA3 I148M Variant and Age at Infection in Determining Fibrosis Progression in Chronic Hepatitis C

BACKGROUND AND AIMS: The PNPLA3 I148M sequence variant favors hepatic lipid accumulation and confers susceptibility to hepatic fibrosis and hepatocellular carcinoma. The aim of this study was to estimate the effect size of homozygosity for the PNPLA3 I148M variant (148M/M) on the fibrosis progressio...

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Detaylı Bibliyografya
Asıl Yazarlar: De Nicola, Stella, Dongiovanni, Paola, Aghemo, Alessio, Cheroni, Cristina, D'Ambrosio, Roberta, Pedrazzini, Michele, Marabita, Francesco, Donnici, Lorena, Maggioni, Marco, Fargion, Silvia, Colombo, Massimo, De Francesco, Raffaele, Valenti, Luca
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149487/
https://ncbi.nlm.nih.gov/pubmed/25171251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106022
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