Interaction between PNPLA3 I148M Variant and Age at Infection in Determining Fibrosis Progression in Chronic Hepatitis C

BACKGROUND AND AIMS: The PNPLA3 I148M sequence variant favors hepatic lipid accumulation and confers susceptibility to hepatic fibrosis and hepatocellular carcinoma. The aim of this study was to estimate the effect size of homozygosity for the PNPLA3 I148M variant (148M/M) on the fibrosis progressio...

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Detalhes bibliográficos
Main Authors: De Nicola, Stella, Dongiovanni, Paola, Aghemo, Alessio, Cheroni, Cristina, D'Ambrosio, Roberta, Pedrazzini, Michele, Marabita, Francesco, Donnici, Lorena, Maggioni, Marco, Fargion, Silvia, Colombo, Massimo, De Francesco, Raffaele, Valenti, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149487/
https://ncbi.nlm.nih.gov/pubmed/25171251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106022
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