Angiopoietin-Like Protein 3 Promotes Preservation of Stemness during Ex Vivo Expansion of Murine Hematopoietic Stem Cells

Allogeneic hematopoietic stem cell (HSC) transplantations from umbilical cord blood or autologous HSCs for gene therapy purposes are hampered by limited number of stem cells. To test the ability to expand HSCs in vitro prior to transplantation, two growth factor cocktails containing stem cell factor...

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Hlavní autoři: Farahbakhshian, Elnaz, Verstegen, Monique M., Visser, Trudi P., Kheradmandkia, Sima, Geerts, Dirk, Arshad, Shazia, Riaz, Noveen, Grosveld, Frank, van Til, Niek P., Meijerink, Jules P. P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149469/
https://ncbi.nlm.nih.gov/pubmed/25170927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105642
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