Angiopoietin-Like Protein 3 Promotes Preservation of Stemness during Ex Vivo Expansion of Murine Hematopoietic Stem Cells

Allogeneic hematopoietic stem cell (HSC) transplantations from umbilical cord blood or autologous HSCs for gene therapy purposes are hampered by limited number of stem cells. To test the ability to expand HSCs in vitro prior to transplantation, two growth factor cocktails containing stem cell factor...

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Detalhes bibliográficos
Main Authors: Farahbakhshian, Elnaz, Verstegen, Monique M., Visser, Trudi P., Kheradmandkia, Sima, Geerts, Dirk, Arshad, Shazia, Riaz, Noveen, Grosveld, Frank, van Til, Niek P., Meijerink, Jules P. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149469/
https://ncbi.nlm.nih.gov/pubmed/25170927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105642
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