GLP-1 (7–36) amide restores myocardial insulin sensitivity and prevents the progression of heart failure in senescent beagles

BACKGROUND: We previously demonstrated that older beagles have impaired whole body and myocardial insulin responsiveness (MIR), and that glucagon-like peptide-1 (GLP-1 [7–36] amide) improves MIR in young beagles with dilated cardiomyopathy (DCM). Here, we sought to determine if aging alone predispos...

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Autores principales: Chen, Melissa, Angeli, Franca S, Shen, You-tang, Shannon, Richard P
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149213/
https://ncbi.nlm.nih.gov/pubmed/25078106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-014-0115-x
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