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The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse

The histone modifying complexes PRC2 and TrxG/MLL play pivotal roles in determining the activation state of genes controlling pluripotency, lineage commitment, and cell differentiation. Long non-coding RNAs (lncRNAs) can bind to either complex, and some have been shown to act as modulators of PRC2 o...

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Autores principales: Grote, Phillip, Wittler, Lars, Währisch, Sandra, Hendrix, David, Beisaw, Arica, Macura, Karol, Bläss, Gaby, Kellis, Manolis, Werber, Martin, Herrmann, Bernhard G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149175/
https://ncbi.nlm.nih.gov/pubmed/23369715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.12.012
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