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BRACHYURY directs histone acetylation to target loci during mesoderm development

T‐box transcription factors play essential roles in multiple aspects of vertebrate development. Here, we show that cooperative function of BRACHYURY (T) with histone‐modifying enzymes is essential for mouse embryogenesis. A single point mutation (T(Y88A)) results in decreased histone 3 lysine 27 ace...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Beisaw, Arica, Tsaytler, Pavel, Koch, Frederic, Schmitz, Sandra U, Melissari, Maria‐Theodora, Senft, Anna D, Wittler, Lars, Pennimpede, Tracie, Macura, Karol, Herrmann, Bernhard G, Grote, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757217/
https://ncbi.nlm.nih.gov/pubmed/29141987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744201
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