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BRACHYURY directs histone acetylation to target loci during mesoderm development
T‐box transcription factors play essential roles in multiple aspects of vertebrate development. Here, we show that cooperative function of BRACHYURY (T) with histone‐modifying enzymes is essential for mouse embryogenesis. A single point mutation (T(Y88A)) results in decreased histone 3 lysine 27 ace...
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Publicado no: | EMBO Rep |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5757217/ https://ncbi.nlm.nih.gov/pubmed/29141987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744201 |
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