A Nonallergenic Birch Pollen Allergy Vaccine Consisting of Hepatitis PreS–Fused Bet v 1 Peptides Focuses Blocking IgG toward IgE Epitopes and Shifts Immune Responses to a Tolerogenic and Th1 Phenotype

Allergen-specific immunotherapy is the only allergen-specific and disease-modifying treatment for allergy. The construction and characterization of a vaccine for birch pollen allergy is reported. Two nonallergenic peptides, PA and PB, derived from the IgE-reactive areas of the major birch pollen all...

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Autores principales: Marth, Katharina, Breyer, Isabella, Focke-Tejkl, Margarete, Blatt, Katharina, Shamji, Mohamed H., Layhadi, Janice, Gieras, Anna, Swoboda, Ines, Zafred, Domen, Keller, Walter, Valent, Peter, Durham, Stephen R., Valenta, Rudolf
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148560/
https://ncbi.nlm.nih.gov/pubmed/23440415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202441
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