Peptidylarginine Deiminase 4 Contributes to Tumor Necrosis Factor α–Induced Inflammatory Arthritis

OBJECTIVE: Peptidylarginine deiminase 4 (PAD4) is a citrullinating enzyme that has multiple associations with inflammation. In rheumatoid arthritis, PAD4 and protein citrullination are increased in inflamed joints, and anti–citrullinated protein antibodies (ACPAs) form against citrullinated antigens...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shelef, Miriam A., Sokolove, Jeremy, Lahey, Lauren J., Wagner, Catriona A., Sackmann, Eric K., Warner, Thomas F., Wang, Yanming, Beebe, David J., Robinson, William H., Huttenlocher, Anna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148484/
https://ncbi.nlm.nih.gov/pubmed/24497204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38393
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