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Smad3 deficient mice have reduced esophageal fibrosis and angiogenesis in a mouse model of egg induced eosinophilic esophagitis
OBJECTIVES: Eosinophilic esophagitis (EoE) is a food triggered disease associated with esophageal fibrosis and stricture formation in a subset of patients. In this study we utilized a murine model of egg (OVA) induced EoE to determine whether inhibiting TGF-β1 signaling through the Smad3 pathway wou...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148477/ https://ncbi.nlm.nih.gov/pubmed/24590208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0000000000000343 |
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