Intestinal PTGS2 mRNA Levels, PTGS2 Gene Polymorphisms, and Colorectal Carcinogenesis

BACKGROUND & AIMS: Inflammation is a major risk factor for development of colorectal cancer (CRC). Prostaglandin synthase cyclooxygenase-2 (COX-2) encoded by the PTGS2 gene is the rate limiting enzyme in prostaglandin synthesis and therefore plays a distinct role as regulator of inflammation. ME...

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Main Authors: Vogel, Lotte K., Sæbø, Mona, Høyer, Helle, Kopp, Tine Iskov, Vogel, Ulla, Godiksen, Sine, Frenzel, Franz B., Hamfjord, Julian, Bowitz-Lothe, Inger Marie, Johnson, Egil, Kure, Elin H., Andersen, Vibeke
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148233/
https://ncbi.nlm.nih.gov/pubmed/25166592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105254
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