Low ABCB1 Gene Expression Is an Early Event in Colorectal Carcinogenesis

The ABCB1/MDR1 gene product ABCB1/P-glycoprotein is implicated in the development of colorectal cancer (CRC). NFKB1 encodes transcription factors regulating expression of a number of genes including ABCB1. We have previously found association between the ABCB1 C-rs3789243-T polymorphism and CRC risk...

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Bibliographic Details
Main Authors: Andersen, Vibeke, Vogel, Ulla, Godiksen, Sine, Frenzel, Franz B., Sæbø, Mona, Hamfjord, Julian, Kure, Elin, Vogel, Lotte K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747088/
https://ncbi.nlm.nih.gov/pubmed/23977225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072119
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