High ABCC2 and Low ABCG2 Gene Expression Are Early Events in the Colorectal Adenoma-Carcinoma Sequence

Development of colorectal cancer (CRC) may result from a dysfunctional interplay between diet, gut microbes and the immune system. The ABC transport proteins ABCB1 (P-glycoprotein, Multidrug resistance protein 1, MDR1), ABCC2 (MRP2) and ABCG2 (BCRP) are involved in transport of various compounds acr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Andersen, Vibeke, Vogel, Lotte K, Kopp, Tine Iskov, Sæbø, Mona, Nonboe, Annika W., Hamfjord, Julian, Kure, Elin H., Vogel, Ulla
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368545/
https://ncbi.nlm.nih.gov/pubmed/25793771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119255
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