Ku-Mediated Coupling of DNA Cleavage and Repair during Programmed Genome Rearrangements in the Ciliate Paramecium tetraurelia

During somatic differentiation, physiological DNA double-strand breaks (DSB) can drive programmed genome rearrangements (PGR), during which DSB repair pathways are mobilized to safeguard genome integrity. Because of their unique nuclear dimorphism, ciliates are powerful unicellular eukaryotic models...

Full description

Saved in:
Bibliographic Details
Main Authors: Marmignon, Antoine, Bischerour, Julien, Silve, Aude, Fojcik, Clémentine, Dubois, Emeline, Arnaiz, Olivier, Kapusta, Aurélie, Malinsky, Sophie, Bétermier, Mireille
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148214/
https://ncbi.nlm.nih.gov/pubmed/25166013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004552
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items