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Ku-Mediated Coupling of DNA Cleavage and Repair during Programmed Genome Rearrangements in the Ciliate Paramecium tetraurelia

During somatic differentiation, physiological DNA double-strand breaks (DSB) can drive programmed genome rearrangements (PGR), during which DSB repair pathways are mobilized to safeguard genome integrity. Because of their unique nuclear dimorphism, ciliates are powerful unicellular eukaryotic models...

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Hlavní autoři: Marmignon, Antoine, Bischerour, Julien, Silve, Aude, Fojcik, Clémentine, Dubois, Emeline, Arnaiz, Olivier, Kapusta, Aurélie, Malinsky, Sophie, Bétermier, Mireille
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148214/
https://ncbi.nlm.nih.gov/pubmed/25166013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004552
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