Highly Precise and Developmentally Programmed Genome Assembly in Paramecium Requires Ligase IV–Dependent End Joining

During the sexual cycle of the ciliate Paramecium, assembly of the somatic genome includes the precise excision of tens of thousands of short, non-coding germline sequences (Internal Eliminated Sequences or IESs), each one flanked by two TA dinucleotides. It has been reported previously that these g...

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Detalhes bibliográficos
Main Authors: Kapusta, Aurélie, Matsuda, Atsushi, Marmignon, Antoine, Ku, Michael, Silve, Aude, Meyer, Eric, Forney, James D., Malinsky, Sophie, Bétermier, Mireille
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077386/
https://ncbi.nlm.nih.gov/pubmed/21533177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002049
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