Highly precise and developmentally programmed genome assembly in Paramecium requires ligase IV-dependent end joining.

During the sexual cycle of the ciliate Paramecium, assembly of the somatic genome includes the precise excision of tens of thousands of short, non-coding germline sequences (Internal Eliminated Sequences or IESs), each one flanked by two TA dinucleotides. It has been reported previously that these g...

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Hlavní autoři: Aurélie Kapusta, Atsushi Matsuda, Antoine Marmignon, Michael Ku, Aude Silve, Eric Meyer, James D Forney, Sophie Malinsky, Mireille Bétermier
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2011-04-01
Edice:PLoS Genetics
On-line přístup:http://europepmc.org/articles/PMC3077386?pdf=render
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