Alterations in Insulin-Signaling and Coagulation Pathways in Platelets during Hyperglycemia-Hyperinsulinemia in Healthy Non-Diabetic Subject

INTRODUCTION: Diabetes mellitus (DM) is a prothrombotic and proinflammatory state. Hyperglycemia (HG) is encountered even in patients without DM. We have shown that combined HG and hyperinsulinemia (HI) in healthy non-diabetic subjects increased circulating tissue factor (TF) and thrombin generation...

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Main Authors: Rao, A. Koneti, Freishtat, Robert J, Jalagadugula, Gauthami, Singh, Anamika, Mao, Guangfen, Wiles, Andrew, Cheung, Peter, Boden, Guenther
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148207/
https://ncbi.nlm.nih.gov/pubmed/25042561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2014.06.029
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