Central P2Y(12) receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents

In this study the role of P2Y(12) receptors (P2Y(12)R) was explored in rodent models of inflammatory and neuropathic pain and in acute thermal nociception. In correlation with their activity to block the recombinant human P2Y(12)R, the majority of P2Y(12)R antagonists alleviated mechanical hyperalge...

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Autors principals: Horváth, Gergely, Gölöncsér, Flóra, Csölle, Cecilia, Király, Kornél, Andó, Rómeó D., Baranyi, Mária, Koványi, Bence, Máté, Zoltán, Hoffmann, Kristina, Algaier, Irina, Baqi, Younis, Müller, Christa E., Von Kügelgen, Ivar, Sperlágh, Beáta
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148180/
https://ncbi.nlm.nih.gov/pubmed/24971933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.06.011
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