Central P2Y(12) receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents

In this study the role of P2Y(12) receptors (P2Y(12)R) was explored in rodent models of inflammatory and neuropathic pain and in acute thermal nociception. In correlation with their activity to block the recombinant human P2Y(12)R, the majority of P2Y(12)R antagonists alleviated mechanical hyperalge...

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Detalhes bibliográficos
Main Authors: Horváth, Gergely, Gölöncsér, Flóra, Csölle, Cecilia, Király, Kornél, Andó, Rómeó D., Baranyi, Mária, Koványi, Bence, Máté, Zoltán, Hoffmann, Kristina, Algaier, Irina, Baqi, Younis, Müller, Christa E., Von Kügelgen, Ivar, Sperlágh, Beáta
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148180/
https://ncbi.nlm.nih.gov/pubmed/24971933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.06.011
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