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Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease

BACKGROUND: Previous studies indicate a role of P2X(7 )receptors in processes that lead to neuronal death. The main objective of our study was to examine whether genetic deletion or pharmacological blockade of P2X(7 )receptors influenced dopaminergic cell death in various models of Parkinson's...

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Main Authors: Hracskó, Zsuzsanna, Baranyi, Mária, Csölle, Cecilia, Gölöncsér, Flóra, Madarász, Emilia, Kittel, Ágnes, Sperlágh, Beáta
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113297/
https://ncbi.nlm.nih.gov/pubmed/21542899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-28
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