Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation

Cancer cells with self-renewal and tumor-initiating capacity, either quiescent (cancer stem cells, CSCs) or proliferating (cancer stem-like cells, CSLCs), are now deemed responsible for the pervasive therapy resistance of pancreatic cancer, one of the deadliest human cancers characterized by high pr...

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Autors principals: Okada, Masashi, Shibuya, Keita, Sato, Atsushi, Seino, Shizuka, Suzuki, Shuhei, Seino, Manabu, Kitanaka, Chifumi
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148125/
https://ncbi.nlm.nih.gov/pubmed/24947996
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