Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients

The role of Ribonucleotide reductase (RR) subunits in different cancers has been intensively studied in our laboratory. RRM2B was identified as a p53-inducible RR subunit that involves in various critical cellular mechanisms such as cell cycle regulation, DNA repair and replication, and mitochondria...

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Bibliographic Details
Main Authors: Cho, Er-Chieh, Kuo, Mei-Ling, Liu, Xiyong, Yang, Lixin, Hsieh, Yi-Chen, Wang, Jinghan, Cheng, Yawen, Yen, Yun
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148103/
https://ncbi.nlm.nih.gov/pubmed/24947616
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