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Capturing the metabolomic diversity of KRAS mutants in non-small-cell lung cancer cells

In non-small-cell lung cancer (NSCLC), one-fifth of patients have KRAS mutations, which are considered a negative predictive factor to first-line therapy. Evidence is emerging that not all KRAS mutations have the same biological activities and possible remodeling of cell metabolism by KRAS activatio...

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Autors principals: Brunelli, Laura, Caiola, Elisa, Marabese, Mirko, Broggini, Massimo, Pastorelli, Roberta
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148094/
https://ncbi.nlm.nih.gov/pubmed/24952473
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